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This belief that indicas, sativas, and hybrids deliver distinct effects is so deeply rooted in mainstream cannabis culture that budtenders typically begin their strain recommendations by asking you which of these three types you prefer. But if you look at the chemical "ingredients" inside of indicas and sativas - that is, terpenes and cannabinoids (more on that below) - you'll notice there aren't clear patterns to explain why one type would be inherently sedating and the other uplifting. We know that indica and sativa cannabis strains can look differently, but this distinction is primarily only useful to cannabis growers.
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